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Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis
Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703399/ https://www.ncbi.nlm.nih.gov/pubmed/23844301 http://dx.doi.org/10.1155/2013/912409 |
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author | Kontoangelos, Konstantinos A. Kouzoupis, Anastasios V. Ferentinos, Panagiotis P. Xynos, Ioannis D. Sipsas, Nikolaos V. Papadimitriou, George N. |
author_facet | Kontoangelos, Konstantinos A. Kouzoupis, Anastasios V. Ferentinos, Panagiotis P. Xynos, Ioannis D. Sipsas, Nikolaos V. Papadimitriou, George N. |
author_sort | Kontoangelos, Konstantinos A. |
collection | PubMed |
description | Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opioids, we administered pregabalin at a dose of 300 mg as an analgesic agent while opioids were discontinued. Findings. Pain symptoms improved progressively, and opioids were gradually discontinued without any withdrawal symptoms reported. Conclusions. Pregabalin is potentially useful in the management of pain in patients with AS while effectively managing the discontinuation of opioid treatment. |
format | Online Article Text |
id | pubmed-3703399 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37033992013-07-10 Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis Kontoangelos, Konstantinos A. Kouzoupis, Anastasios V. Ferentinos, Panagiotis P. Xynos, Ioannis D. Sipsas, Nikolaos V. Papadimitriou, George N. Case Rep Psychiatry Case Report Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opioids, we administered pregabalin at a dose of 300 mg as an analgesic agent while opioids were discontinued. Findings. Pain symptoms improved progressively, and opioids were gradually discontinued without any withdrawal symptoms reported. Conclusions. Pregabalin is potentially useful in the management of pain in patients with AS while effectively managing the discontinuation of opioid treatment. Hindawi Publishing Corporation 2013 2013-06-17 /pmc/articles/PMC3703399/ /pubmed/23844301 http://dx.doi.org/10.1155/2013/912409 Text en Copyright © 2013 Konstantinos A. Kontoangelos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kontoangelos, Konstantinos A. Kouzoupis, Anastasios V. Ferentinos, Panagiotis P. Xynos, Ioannis D. Sipsas, Nikolaos V. Papadimitriou, George N. Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis |
title | Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis |
title_full | Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis |
title_fullStr | Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis |
title_full_unstemmed | Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis |
title_short | Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis |
title_sort | pregabalin for opioid-refractory pain in a patient with ankylosing spondylitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703399/ https://www.ncbi.nlm.nih.gov/pubmed/23844301 http://dx.doi.org/10.1155/2013/912409 |
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