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Constitutive Proteasomal Degradation of TWIST-1 in Epithelial Ovarian Cancer Stem Cells Impacts Differentiation and Metastatic Potential
Epithelial-mesenchymal transition (EMT) is a critical process for embryogenesis but is abnormally activated during cancer metastasis and recurrence. This process enables epithelial cancer cells to acquire mobility and traits associated with stemness. It is unknown whether epithelial stem cells or ep...
Autores principales: | Yin, Gang, Alvero, Ayesha B., Craveiro, Vinicius, Holmberg, Jennie C., Fu, Han-Hsuan, Montagna, Michele K., Yang, Yang, Chefetz-Menaker, Ilana, Nuti, Sudhakar, Rossi, Michael, Silasi, Dan-Arin, Rutherford, Thomas, Mor, Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703656/ https://www.ncbi.nlm.nih.gov/pubmed/22349827 http://dx.doi.org/10.1038/onc.2012.33 |
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