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Targeting the Vasculature of Colorectal Carcinoma with a Fused Protein of (RGD)(3)-tTF

Purpose. Truncated tissue factor (tTF) fusion protein targeting tumor vasculature can induce tumor vascular thrombosis and necrosis. Here, we generated (RGD)(3)-tTF in which three arginine-glycine-aspartic (RGD) targeting integrin α (v) β (3) and tTF induce blood coagulation in tumor vessels. Method...

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Detalles Bibliográficos
Autores principales:	Huang, Zheng-jie, Zhao, Yilin, Luo, Wei-yuan, You, Jun, Li, Shui-wen, Yi, Wen-cheng, Wang, Sheng-yu, Yan, Jiang-hua, Luo, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703901/ https://www.ncbi.nlm.nih.gov/pubmed/23861656 http://dx.doi.org/10.1155/2013/637086

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