Cargando…

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Activation of mammalian target of rapamycin 1 (mTORC1) by nutrients, insulin and leptin leads to appetite suppression (anorexia). Contrastingly, increased AMP-activated protein kinase (AMPK) activity by ghrelin promotes appetite (orexia). However, the interplay between these mechanisms remains poorl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watterson, Kenneth R., Bestow, Dawn, Gallagher, Jennifer, Hamilton, D. Lee, Ashford, Fiona B., Meakin, Paul J., Ashford, Michael L.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2012
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704126/ https://www.ncbi.nlm.nih.gov/pubmed/22456226 http://dx.doi.org/10.1159/000334144

Ejemplares similares

Inhibition of hypothalamic MCT1 expression increases food intake and alters orexigenic and anorexigenic neuropeptide expression
por: Elizondo-Vega, Roberto, et al.
Publicado: (2016)

MCT2 Expression and Lactate Influx in Anorexigenic and Orexigenic Neurons of the Arcuate Nucleus
por: Cortes-Campos, Christian, et al.
Publicado: (2013)

Inhibition of Hypothalamic MCT4 and MCT1–MCT4 Expressions Affects Food Intake and Alters Orexigenic and Anorexigenic Neuropeptide Expressions
por: Elizondo-Vega, Roberto, et al.
Publicado: (2019)

Modulation of orexigenic and anorexigenic peptides gene expression in the rat DVC and hypothalamus by acute immobilization stress
por: Chigr, Fatiha, et al.
Publicado: (2014)

Prenatal and early postnatal food restrictions cause changes in brain oxidative status and orexigenic/anorexigenic hormones in the offspring of rats: prevention by quercetin and kaempferol
por: Anachuna, Kenneth Kelechi, et al.
Publicado: (2020)

Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes
por: Hamilton, D. Lee, et al.
Publicado: (2014)

Glucose Increase DAGLα Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose
por: Palma-Chavez, Alejandra, et al.
Publicado: (2019)

Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin
por: Martins, Luís, et al.
Publicado: (2012)

Hypothalamic Agouti‐Related Peptide mRNA is Elevated During Natural and Stress‐Induced Anorexia
por: Dunn, I. C., et al.
Publicado: (2015)

Asprosin is a centrally-acting orexigenic hormone
por: Duerrschmid, Clemens, et al.
Publicado: (2017)

Involvement of Mechanistic Target of Rapamycin (mTOR) in Valine Orexigenic Effects in Rainbow Trout
por: Comesaña, Sara, et al.
Publicado: (2022)

(−)-Epigallocatechin-3-gallate induces secretion of anorexigenic gut hormones
por: Song, Won-Young, et al.
Publicado: (2015)

Hypothalamic Ceramide Levels Regulated by CPT1C Mediate the Orexigenic Effect of Ghrelin
por: Ramírez, Sara, et al.
Publicado: (2013)

Fasting induces remodeling of the orexigenic projections from the arcuate nucleus to the hypothalamic paraventricular nucleus, in a growth hormone secretagogue receptor–dependent manner
por: Cabral, Agustina, et al.
Publicado: (2019)

Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour
por: Beall, C., et al.
Publicado: (2012)

Dietary phosphorus level regulates appetite through modulation of gut and hypothalamic expression of anorexigenic genes in broiler chickens
por: Aderibigbe, A.S., et al.
Publicado: (2021)

A Single Dose of Ginkgo biloba Extract Induces Gene Expression of Hypothalamic Anorexigenic Effectors in Male Rats
por: Machado, Meira M. F., et al.
Publicado: (2021)

Sex differences in basal hypothalamic anorectic and orexigenic gene expression and the effect of quantitative and qualitative food restriction
por: Caughey, S. D., et al.
Publicado: (2018)

Lipocalin-2 is an anorexigenic signal in primates
por: Petropoulou, Peristera-Ioanna, et al.
Publicado: (2020)

Olanzapine-Induced Hyperphagia and Weight Gain Associate with Orexigenic Hypothalamic Neuropeptide Signaling without Concomitant AMPK Phosphorylation
por: Fernø, Johan, et al.
Publicado: (2011)

Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions
por: Gupta, Deepali, et al.
Publicado: (2021)

Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activities
por: Hu, Yixuan, et al.
Publicado: (2023)

The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Relevance to Food Intake and Nutritional Status in Patients with Anorexia Nervosa and Bulimia Nervosa
por: Smitka, Kvido, et al.
Publicado: (2013)

The Orexigenic Force of Olfactory Palatable Food Cues in Rats
por: Peris-Sampedro, Fiona, et al.
Publicado: (2021)

An orexigenic subnetwork within the human hippocampus
por: Barbosa, Daniel A. N., et al.
Publicado: (2023)

The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation
por: Kent, Brianne A., et al.
Publicado: (2015)

LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue
por: Shankar, Kripa, et al.
Publicado: (2021)

OR23-3 Hunger Hormone Asprosin Activates Orexigenic Neurons via SK Currents
por: Feng, Bing, et al.
Publicado: (2022)

Hypothalamic Expression of Melanocortin-4 Receptor and Agouti-related Peptide mRNAs During the Estrous Cycle of Rats
por: Zandi, Mohammad Reza, et al.
Publicado: (2014)

Enhanced Ghrelin Levels and Hypothalamic Orexigenic AgRP and NPY Neuropeptide Expression in Models of Jejuno-Colonic Short Bowel Syndrome
por: Gillard, Laura, et al.
Publicado: (2016)

Involvement of the CXCL12 System in the Stimulatory Effects of Prenatal Exposure to High-Fat Diet on Hypothalamic Orexigenic Peptides and Behavior in Offspring
por: Poon, Kinning, et al.
Publicado: (2017)

Interactions of Gastrointestinal Peptides: Ghrelin and Its Anorexigenic Antagonists
por: Wisser, Anna-Sophia, et al.
Publicado: (2010)

Xenin is a novel anorexigen in goldfish (Carassius auratus)
por: Kerbel, Brent, et al.
Publicado: (2018)

Recent progress on action and regulation of anorexigenic adipokine leptin
por: Nakagawa, Tadashi, et al.
Publicado: (2023)

Orexigenic Hormone Ghrelin Attenuates Local and Remote Organ Injury after Intestinal Ischemia-Reperfusion
por: Wu, Rongqian, et al.
Publicado: (2008)

Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle
por: Shiuchi, Tetsuya, et al.
Publicado: (2021)

Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge
por: Dadak, Selma, et al.
Publicado: (2017)

Placentation in the paca (Agouti paca L)
por: Bonatelli, Marina, et al.
Publicado: (2005)

The Food-Contaminant Deoxynivalenol Modifies Eating by Targeting Anorexigenic Neurocircuitry
por: Girardet, Clémence, et al.
Publicado: (2011)

Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4
por: Lee, Shin J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_igt4ogk3hprtq87le9c06f5cm6