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Lyophilized phytosomal nanocarriers as platforms for enhanced diosmin delivery: optimization and ex vivo permeation

Diosmin (DSN) is an outstanding phlebotonic flavonoid with a tolerable potential for the treatment of colon and hepatocellular carcinoma. Being highly insoluble, DSN bioavailability suffers from high inter-subject variation due to variable degrees of permeation. This work endeavored to develop novel...

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Detalles Bibliográficos
Autores principales: Freag, May S, Elnaggar, Yosra SR, Abdallah, Ossama Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704438/
https://www.ncbi.nlm.nih.gov/pubmed/23861584
http://dx.doi.org/10.2147/IJN.S45231