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Ventricular orexin-A (hypocretin-1) levels correlate with rapid-eye-movement sleep without atonia in Parkinson’s disease

OBJECTIVE: Patients with Parkinson’s disease frequently complain of sleep disturbances and loss of muscle atonia during rapid-eye-movement (REM) sleep is not rare. The orexin-A (hypocretin-1) hypothalamic system plays a central role in controlling REM sleep. Loss of orexin neurons results in narcole...

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Detalles Bibliográficos
Autores principales:	Bridoux, Agathe, Moutereau, Stephane, Covali-Noroc, Ala, Margarit, Laurent, Palfi, Stephane, Nguyen, Jean-Paul, Lefaucheur, Jean-Pascal, Césaro, Pierre, d’Ortho, Marie-Pia, Drouot, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704548/ https://www.ncbi.nlm.nih.gov/pubmed/23847436 http://dx.doi.org/10.2147/NSS.S41245

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