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NRAS and BRAF Mutations in Melanoma-Associated Nevi and Uninvolved Nevi

According to the prevailing multistep model of melanoma development, oncogenic BRAF or NRAS mutations are crucial initial events in melanoma development. It is not known whether melanocytic nevi that are found in association with a melanoma are more likely to carry BRAF or NRAS mutations than uninvo...

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Detalles Bibliográficos
Autores principales: Tschandl, Philipp, Berghoff, Anna Sophie, Preusser, Matthias, Burgstaller-Muehlbacher, Sebastian, Pehamberger, Hubert, Okamoto, Ichiro, Kittler, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704624/
https://www.ncbi.nlm.nih.gov/pubmed/23861977
http://dx.doi.org/10.1371/journal.pone.0069639

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