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A Novel 3D Label-Free Monitoring System of hES-Derived Cardiomyocyte Clusters: A Step Forward to In Vitro Cardiotoxicity Testing

Unexpected adverse effects on the cardiovascular system remain a major challenge in the development of novel active pharmaceutical ingredients (API). To overcome the current limitations of animal-based in vitro and in vivo test systems, stem cell derived human cardiomyocyte clusters (hCMC) offer the...

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Detalles Bibliográficos
Autores principales:	Jahnke, Heinz-Georg, Steel, Daniella, Fleischer, Stephan, Seidel, Diana, Kurz, Randy, Vinz, Silvia, Dahlenborg, Kerstin, Sartipy, Peter, Robitzki, Andrea A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704625/ https://www.ncbi.nlm.nih.gov/pubmed/23861955 http://dx.doi.org/10.1371/journal.pone.0068971

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