Cargando…

UV-Induced Nuclear Import of XPA Is Mediated by Importin-α4 in An ATR-Dependent Manner

Xeroderma pigmentosum Group A (XPA) is a crucial factor in mammalian nucleotide excision repair (NER) and nuclear import of XPA from the cytoplasm for NER is regulated in cellular DNA damage responses in S-phase. In this study, experiments were carried out to determine the transport mechanisms that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhengke, Musich, Phillip R., Cartwright, Brian M., Wang, Hui, Zou, Yue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704644/ https://www.ncbi.nlm.nih.gov/pubmed/23861882 http://dx.doi.org/10.1371/journal.pone.0068297

Ejemplares similares

XPA-Mediated Regulation of Global Nucleotide Excision Repair by ATR Is p53-Dependent and Occurs Primarily in S-Phase
por: Li, Zhengke, et al.
Publicado: (2011)

PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses
por: Makinwa, Yetunde, et al.
Publicado: (2020)

Nuclear importin α and its physiological importance
por: Miyamoto, Yoichi, et al.
Publicado: (2012)

DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair
por: Serrano, Moises A., et al.
Publicado: (2012)

A new structural insight into XPA–DNA interactions
por: Hilton, Benjamin, et al.
Publicado: (2014)

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner
por: Lowe, Alan R, et al.
Publicado: (2015)

Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor
por: Herold, Andrea, et al.
Publicado: (1998)

Phosphorylation-Dependent Pin1 Isomerization of ATR: Its Role in Regulating ATR’s Anti-apoptotic Function at Mitochondria, and the Implications in Cancer
por: Makinwa, Yetunde, et al.
Publicado: (2020)

Nuclear import time and transport efficiency depend on importin β concentration
por: Yang, Weidong, et al.
Publicado: (2006)

Stimulated nuclear import by β-like importins
por: Flores, Karen, et al.
Publicado: (2013)

The adapter importin-α provides flexible control of nuclear import at the expense of efficiency
por: Riddick, Greg, et al.
Publicado: (2007)

A systems analysis of importin-α–β mediated nuclear protein import
por: Riddick, Gregory, et al.
Publicado: (2005)

Promotion of importin α–mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3
por: Faul, Christian, et al.
Publicado: (2005)

An actin-regulated importin α/β-dependent extended bipartite NLS directs nuclear import of MRTF-A
por: Pawłowski, Rafał, et al.
Publicado: (2010)

Cellular stresses induce the nuclear accumulation of importin α and cause a conventional nuclear import block
por: Miyamoto, Yoichi, et al.
Publicado: (2004)

ATR prevents Ca(2+) overload‐induced necrotic cell death through phosphorylation‐mediated inactivation of PARP1 without DNA damage signaling
por: Li, Zhengke, et al.
Publicado: (2021)

Karyopherin α7 (KPNA7), a divergent member of the importin α family of nuclear import receptors
por: Kelley, Joshua B, et al.
Publicado: (2010)

The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
por: Jung, Hunmin, et al.
Publicado: (2020)

Maternal Nanos inhibits Importin-α2/Pendulin-dependent nuclear import to prevent somatic gene expression in the Drosophila germline
por: Asaoka, Miho, et al.
Publicado: (2019)

Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-β1
por: Cimica, Velasco, et al.
Publicado: (2011)

XPA: DNA Repair Protein of Significant Clinical Importance
por: Borszéková Pulzová, Lucia, et al.
Publicado: (2020)

Importin α: functions as a nuclear transport factor and beyond
por: OKA, Masahiro, et al.
Publicado: (2018)

The nuclear import of Frizzled2-C by Importins-β11 and α2 promotes postsynaptic development
por: Mosca, Timothy J., et al.
Publicado: (2010)

Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme
por: Moutty, Marie Christine, et al.
Publicado: (2011)

Withdrawal: Sirtuin 1-mediated deacetylation of XPA DNA repair protein enhances its interaction with ATR protein and promotes cAMP-induced DNA repair of UV damage
por: Jarrett, Stuart G., et al.
Publicado: (2021)

Yeast importin-β is required for nuclear import of the Mig2 repressor
por: Fernández-Cid, Alejandra, et al.
Publicado: (2012)

Importin α5 negatively regulates importin β1-mediated nuclear import of Newcastle disease virus matrix protein and viral replication and pathogenicity in chicken fibroblasts
por: Duan, Zhiqiang, et al.
Publicado: (2018)

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons
por: Döhner, Katinka, et al.
Publicado: (2018)

Gradient of Increasing Affinity of Importin β for Nucleoporins along the Pathway of Nuclear Import
por: Ben-Efraim, Iris, et al.
Publicado: (2001)

Higher Nucleoporin-Importinβ Affinity at the Nuclear Basket Increases Nucleocytoplasmic Import
por: Azimi, Mohammad, et al.
Publicado: (2013)

Nuclear localisation sequences of chloride intracellular channels 1 and 4 facilitate nuclear import via interactions with import mediator importin‐α: An empirical and theoretical perspective
por: Færch, Olga, et al.
Publicado: (2022)

Deciphering the Binding of the Nuclear Localization Sequence of Myc Protein to the Nuclear Carrier Importin α3
por: Rizzuti, Bruno, et al.
Publicado: (2022)

Recognition of the TDP-43 nuclear localization signal by importin α1/β
por: Doll, Steven G., et al.
Publicado: (2022)

Human Enzyme PADI4 Binds to the Nuclear Carrier Importin α3
por: Neira, José L., et al.
Publicado: (2022)

Acetylation of the nuclear localization signal in Ku70 diminishes the interaction with importin-α
por: Fujimoto, Hirofumi, et al.
Publicado: (2022)

HIV-1 exploits importin 7 to maximize nuclear import of its DNA genome
por: Zaitseva, Lyubov, et al.
Publicado: (2009)

Importin 7 and Nup358 Promote Nuclear Import of the Protein Component of Human Telomerase
por: Frohnert, Cornelia, et al.
Publicado: (2014)

Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins
por: Eldridge, Matthew J. G., et al.
Publicado: (2020)

Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP
por: García-García, María, et al.
Publicado: (2022)

The Drosophila Importin-α3 Is Required for Nuclear Import of Notch In Vivo and It Displays Synergistic Effects with Notch Receptor on Cell Proliferation
por: Sachan, Nalani, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9vg180ulhdivairoo3g10259f2