Synthesis, docking and acetylcholinesterase inhibitory assessment of 2-(2-(4-Benzylpiperazin-1-yl)ethyl)isoindoline-1,3-dione derivatives with potential anti-Alzheimer effects

BACKGROUND: Alzheimer’s disease (AD) as neurodegenerative disorder, is the most common form of dementia accounting for about 50-60% of the overall cases of dementia among persons over 65 years of age. Low acetylcholine (ACh) concentration in hippocampus and cortex areas of the brain is one of the ma...

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Detalles Bibliográficos
Autores principales: Mohammadi-Farani, Ahmad, Ahmadi, Aram, Nadri, Hamid, Aliabadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704662/
https://www.ncbi.nlm.nih.gov/pubmed/23758724
http://dx.doi.org/10.1186/2008-2231-21-47

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