Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?

Bovine papillomaviruses (BPVs) induce hyperplastic and tumoral lesions not only in cows but also in other different animal species. The transforming activity of BPVs is due to its major E5 oncogene. Recent studies have highlighted the role of E5 in cancer development but very little is known about E...

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Autor principal: Borzacchiello, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704702/
https://www.ncbi.nlm.nih.gov/pubmed/23829702
http://dx.doi.org/10.1186/1750-9378-8-26
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author Borzacchiello, Giuseppe
author_facet Borzacchiello, Giuseppe
author_sort Borzacchiello, Giuseppe
collection PubMed
description Bovine papillomaviruses (BPVs) induce hyperplastic and tumoral lesions not only in cows but also in other different animal species. The transforming activity of BPVs is due to its major E5 oncogene. Recent studies have highlighted the role of E5 in cancer development but very little is known about E6 and E7 oncogenes. In this letter we argue for the need of investigating E6 as well as E7 to better understand the role of these two oncogenes during carcinogenesis.
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spelling pubmed-37047022013-07-09 Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party? Borzacchiello, Giuseppe Infect Agent Cancer Letter to the Editor Bovine papillomaviruses (BPVs) induce hyperplastic and tumoral lesions not only in cows but also in other different animal species. The transforming activity of BPVs is due to its major E5 oncogene. Recent studies have highlighted the role of E5 in cancer development but very little is known about E6 and E7 oncogenes. In this letter we argue for the need of investigating E6 as well as E7 to better understand the role of these two oncogenes during carcinogenesis. BioMed Central 2013-07-05 /pmc/articles/PMC3704702/ /pubmed/23829702 http://dx.doi.org/10.1186/1750-9378-8-26 Text en Copyright © 2013 Borzacchiello; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Borzacchiello, Giuseppe
Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?
title Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?
title_full Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?
title_fullStr Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?
title_full_unstemmed Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?
title_short Bovine papillomavirus on the scene of crime: is E5 oncogene the only guilty party?
title_sort bovine papillomavirus on the scene of crime: is e5 oncogene the only guilty party?
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704702/
https://www.ncbi.nlm.nih.gov/pubmed/23829702
http://dx.doi.org/10.1186/1750-9378-8-26
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