Cargando…

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum

BACKGROUND: The carbon metabolism of the blood stages of Plasmodium falciparum, comprising rapidly dividing asexual stages and non-dividing gametocytes, is thought to be highly streamlined, with glycolysis providing most of the cellular ATP. However, these parasitic stages express all the enzymes ne...

Descripción completa

Detalles Bibliográficos
Autores principales:	MacRae, James I, Dixon, Matthew WA, Dearnley, Megan K, Chua, Hwa H, Chambers, Jennifer M, Kenny, Shannon, Bottova, Iveta, Tilley, Leann, McConville, Malcolm J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704724/ https://www.ncbi.nlm.nih.gov/pubmed/23763941 http://dx.doi.org/10.1186/1741-7007-11-67

Ejemplares similares

Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking
por: Kennedy, Kit, et al.
Publicado: (2019)

Initiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection
por: Farid, Ryan, et al.
Publicado: (2017)

Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites
por: Chua, Ming Jang, et al.
Publicado: (2018)

Role of Melatonin in the Synchronization of Asexual Forms in the Parasite Plasmodium falciparum
por: Singh, Maneesh Kumar, et al.
Publicado: (2020)

The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum
por: Dumont, Laure, et al.
Publicado: (2019)

Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast
por: Shears, Melanie J., et al.
Publicado: (2016)

A Plasmodium falciparum C-mannosyltransferase is dispensable for parasite asexual blood stage development
por: López-Gutiérrez, Borja, et al.
Publicado: (2019)

Cultivation of Asexual Intraerythrocytic Stages of Plasmodium falciparum
por: Basco, Leonardo K.
Publicado: (2023)

Extensive Metabolic Remodeling Differentiates Non-pathogenic and Pathogenic Growth Forms of the Dimorphic Pathogen Talaromyces marneffei
por: Pasricha, Shivani, et al.
Publicado: (2017)

Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite
por: Zhang, Yao, et al.
Publicado: (2015)

Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass
por: Duffy, Michael F., et al.
Publicado: (2022)

Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum
Publicado: (1984)

Inhibitory Potential of Prodomain of Plasmodium falciparum Protease Serine Repeat Antigen 5 for Asexual Blood Stages of Parasite
por: Alam, Asrar, et al.
Publicado: (2012)

The Plasmodium falciparum, Nima-related kinase Pfnek-4: a marker for asexual parasites committed to sexual differentiation
por: Reininger, Luc, et al.
Publicado: (2012)

Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites
por: van Biljon, Riëtte, et al.
Publicado: (2018)

Molecular Markers for Sensitive Detection of Plasmodium falciparum Asexual Stage Parasites and their Application in a Malaria Clinical Trial
por: Tadesse, Fitsum G., et al.
Publicado: (2017)

Transcription Sites Are Developmentally Regulated during the Asexual Cycle of Plasmodium falciparum
por: Moraes, Carolina B., et al.
Publicado: (2013)

Internalization of Erythrocyte Acylpeptide Hydrolase Is Required for Asexual Replication of Plasmodium falciparum
por: Elahi, Rubayet, et al.
Publicado: (2019)

Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum
por: Elahi, Rubayet, et al.
Publicado: (2019)

Comparison of detection methods to estimate asexual Plasmodium falciparum parasite prevalence and gametocyte carriage in a community survey in Tanzania
por: Mwingira, Felista, et al.
Publicado: (2014)

Shelph2, a bacterial-like phosphatase of the malaria parasite Plasmodium falciparum, is dispensable during asexual blood stage
por: Miliu, Alexandra, et al.
Publicado: (2017)

Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites
por: Ressurreição, Margarida, et al.
Publicado: (2020)

Repurposing the mitotic machinery to drive cellular elongation and chromatin reorganisation in Plasmodium falciparum gametocytes
por: Li, Jiahong, et al.
Publicado: (2022)

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage
por: Tibúrcio, Marta, et al.
Publicado: (2015)

Non‐canonical metabolic pathways in the malaria parasite detected by isotope‐tracing metabolomics
por: Cobbold, Simon A, et al.
Publicado: (2021)

Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum
por: Dickerman, Benjamin K., et al.
Publicado: (2016)

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites
por: Charnaud, Sarah C., et al.
Publicado: (2017)

Ned-19 inhibition of parasite growth and multiplication suggests a role for NAADP mediated signalling in the asexual development of Plasmodium falciparum
por: Suárez-Cortés, Pablo, et al.
Publicado: (2017)

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum
por: López-Barragán, María J, et al.
Publicado: (2011)

Genome-wide regulatory dynamics of translation in the Plasmodium falciparum asexual blood stages
por: Caro, Florence, et al.
Publicado: (2014)

Widespread occurrence of lysine methylation in Plasmodium falciparum proteins at asexual blood stages
por: Kaur, Inderjeet, et al.
Publicado: (2016)

The cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development
por: Wezena, Cletus A., et al.
Publicado: (2017)

PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum
por: Jonsdottir, Thorey K., et al.
Publicado: (2023)

Association between alpha-thalassaemia trait, Plasmodium falciparum asexual parasites and gametocyte carriage in a malaria endemic area in Southern Ghana
por: Lamptey, Helena, et al.
Publicado: (2019)

Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites
por: Coetzee, Nanika, et al.
Publicado: (2017)

Challenges of assessing the clinical efficacy of asexual blood-stage Plasmodium falciparum malaria vaccines
por: Sheehy, Susanne H, et al.
Publicado: (2013)

The Basal Complex Protein PfMORN1 Is Not Required for Asexual Replication of Plasmodium falciparum
por: Moran, Colleen J., et al.
Publicado: (2021)

Detection and Quantification of Early-Stage Malaria Parasites in Laboratory Infected Erythrocytes by Attenuated Total Reflectance Infrared Spectroscopy and Multivariate Analysis
por: Khoshmanesh, Aazam, et al.
Publicado: (2014)

Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments
por: Srivastava, Anubhav, et al.
Publicado: (2016)

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance
por: Dogovski, Con, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0bmr0bkjjncsrml3s2fqikkmme