Cargando…

MoniTORing neuronal excitability at the synapse

Mammalian target of rapamycin (mTOR) is a key player at the synapse regulating local translation and long-lasting synaptic plasticity. Now, a new study by Sosanya et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201212089) investigates the molecular mechanism of how mTOR suppresses local pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kepert, Inge, Kiebler, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704992/
https://www.ncbi.nlm.nih.gov/pubmed/23836926
http://dx.doi.org/10.1083/jcb.201304183
_version_ 1782476381678993408
author Kepert, Inge
Kiebler, Michael A.
author_facet Kepert, Inge
Kiebler, Michael A.
author_sort Kepert, Inge
collection PubMed
description Mammalian target of rapamycin (mTOR) is a key player at the synapse regulating local translation and long-lasting synaptic plasticity. Now, a new study by Sosanya et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201212089) investigates the molecular mechanism of how mTOR suppresses local protein synthesis of a key potassium channel at activated synapses.
format Online
Article
Text
id pubmed-3704992
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-37049922014-01-08 MoniTORing neuronal excitability at the synapse Kepert, Inge Kiebler, Michael A. J Cell Biol Reviews Mammalian target of rapamycin (mTOR) is a key player at the synapse regulating local translation and long-lasting synaptic plasticity. Now, a new study by Sosanya et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201212089) investigates the molecular mechanism of how mTOR suppresses local protein synthesis of a key potassium channel at activated synapses. The Rockefeller University Press 2013-07-08 /pmc/articles/PMC3704992/ /pubmed/23836926 http://dx.doi.org/10.1083/jcb.201304183 Text en © 2013 Kepert and Kiebler This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Kepert, Inge
Kiebler, Michael A.
MoniTORing neuronal excitability at the synapse
title MoniTORing neuronal excitability at the synapse
title_full MoniTORing neuronal excitability at the synapse
title_fullStr MoniTORing neuronal excitability at the synapse
title_full_unstemmed MoniTORing neuronal excitability at the synapse
title_short MoniTORing neuronal excitability at the synapse
title_sort monitoring neuronal excitability at the synapse
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704992/
https://www.ncbi.nlm.nih.gov/pubmed/23836926
http://dx.doi.org/10.1083/jcb.201304183
work_keys_str_mv AT kepertinge monitoringneuronalexcitabilityatthesynapse
AT kieblermichaela monitoringneuronalexcitabilityatthesynapse