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The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function

Ca(2+) influx by store-operated Ca(2+) channels (SOCs) mediates all Ca(2+)-dependent cell functions, but excess Ca(2+) influx is highly toxic. The molecular components of SOC are the pore-forming Orai1 channel and the endoplasmic reticulum Ca(2+) sensor STIM1. Slow Ca(2+)-dependent inactivation (SCD...

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Detalles Bibliográficos
Autores principales:	Jha, Archana, Ahuja, Malini, Maléth, József, Moreno, Claudia M., Yuan, Joseph P., Kim, Min Seuk, Muallem, Shmuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704993/ https://www.ncbi.nlm.nih.gov/pubmed/23816623 http://dx.doi.org/10.1083/jcb.201301148

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