Two New Bromophenols with Radical Scavenging Activity from Marine Red Alga Symphyocladia latiuscula

Chemical investigation of a Chinese collection of marine red alga Symphyocladia latiuscula yielded two new highly brominated phenols. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HRMS, 1D and 2D NMR and MS methods. Compounds 1 and 2 were evaluated...

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Detalles Bibliográficos
Autores principales: Xu, Xiuli, Yin, Liyuan, Gao, Lijie, Gao, Junhai, Chen, Junhui, Li, Jingxi, Song, Fuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705374/
https://www.ncbi.nlm.nih.gov/pubmed/23528951
http://dx.doi.org/10.3390/md11030842
Descripción
Sumario:Chemical investigation of a Chinese collection of marine red alga Symphyocladia latiuscula yielded two new highly brominated phenols. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HRMS, 1D and 2D NMR and MS methods. Compounds 1 and 2 were evaluated for radical scavenging capability by 1,1-diphenyl-2-picrylhydrazuyl (DPPH) radical with the IC(50) value of 14.5 and 20.5 μg/mL, respectively.

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