Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis

Three new dolastane diterpenes (1–3) and five previously reported perhydroazulenes were isolated from the organic extracts of the brown alga Dilophus spiralis. The structure elucidation and the assignment of the relative configurations of the isolated natural products were based on extensive analyse...

Descripción completa

Detalles Bibliográficos
Autores principales: Ioannou, Efstathia, Vagias, Constantinos, Roussis, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705391/
https://www.ncbi.nlm.nih.gov/pubmed/23549282
http://dx.doi.org/10.3390/md11041104
_version_ 1782476432833773568
author Ioannou, Efstathia
Vagias, Constantinos
Roussis, Vassilios
author_facet Ioannou, Efstathia
Vagias, Constantinos
Roussis, Vassilios
author_sort Ioannou, Efstathia
collection PubMed
description Three new dolastane diterpenes (1–3) and five previously reported perhydroazulenes were isolated from the organic extracts of the brown alga Dilophus spiralis. The structure elucidation and the assignment of the relative configurations of the isolated natural products were based on extensive analyses of their spectroscopic data, whereas the absolute configuration of metabolite 2 was determined through its chemical conversion to a previously isolated compound of known configuration.
format Online
Article
Text
id pubmed-3705391
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-37053912013-07-09 Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis Ioannou, Efstathia Vagias, Constantinos Roussis, Vassilios Mar Drugs Article Three new dolastane diterpenes (1–3) and five previously reported perhydroazulenes were isolated from the organic extracts of the brown alga Dilophus spiralis. The structure elucidation and the assignment of the relative configurations of the isolated natural products were based on extensive analyses of their spectroscopic data, whereas the absolute configuration of metabolite 2 was determined through its chemical conversion to a previously isolated compound of known configuration. MDPI 2013-04-02 /pmc/articles/PMC3705391/ /pubmed/23549282 http://dx.doi.org/10.3390/md11041104 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Ioannou, Efstathia
Vagias, Constantinos
Roussis, Vassilios
Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
title Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
title_full Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
title_fullStr Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
title_full_unstemmed Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
title_short Isolation and Structure Elucidation of Three New Dolastanes from the Brown Alga Dilophus spiralis
title_sort isolation and structure elucidation of three new dolastanes from the brown alga dilophus spiralis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705391/
https://www.ncbi.nlm.nih.gov/pubmed/23549282
http://dx.doi.org/10.3390/md11041104
work_keys_str_mv AT ioannouefstathia isolationandstructureelucidationofthreenewdolastanesfromthebrownalgadilophusspiralis
AT vagiasconstantinos isolationandstructureelucidationofthreenewdolastanesfromthebrownalgadilophusspiralis
AT roussisvassilios isolationandstructureelucidationofthreenewdolastanesfromthebrownalgadilophusspiralis

Ejemplares similares