The sonic hedgehog pathway mediates brain plasticity and subsequent functional recovery after bone marrow stromal cell treatment of stroke in mice

Bone marrow stromal cells (MSCs) improve neurologic recovery after middle cerebral artery occlusion (MCAo). To examine whether in vivo blockage of the endogenous sonic hedgehog (Shh) pathway affects grafted MSC-induced neurologic benefits, MCAo mice were administered: vehicle (control); cyclopamine...

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Detalles Bibliográficos
Autores principales: Ding, Xiaoshuang, Li, Yi, Liu, Zhongwu, Zhang, Jing, Cui, Yisheng, Chen, Xiaoguang, Chopp, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705435/
https://www.ncbi.nlm.nih.gov/pubmed/23549381
http://dx.doi.org/10.1038/jcbfm.2013.50

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