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Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage

ING2 (inhibitor of growth family member 2) is a component of a chromatin-regulatory complex that represses gene expression and is implicated in cellular processes that promote tumor suppression. However, few direct genomic targets of ING2 have been identified and the mechanism(s) by which ING2 selec...

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Detalles Bibliográficos
Autores principales: Bua, Dennis J., Martin, Gloria Mas, Binda, Olivier, Gozani, Or
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705588/
https://www.ncbi.nlm.nih.gov/pubmed/23823870
http://dx.doi.org/10.1038/srep02137