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In-silico analysis of caspase-3 and -7 proteases from blood-parasitic Schistosoma species (Trematoda) and their human host

Proteolytic enzymes of the caspase family, which reside as latent precursors in most nucleated metazoan cells, are core effectors of apoptosis. Of them, the executioner caspases- 3 and -7 exist within the cytosol as inactive dimers and are activated by a process called dimerization. Caspase inhibiti...

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Detalles Bibliográficos
Autores principales: Kumar, Shakti, Biswal, Devendra Kumar, Tandon, Veena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705615/
https://www.ncbi.nlm.nih.gov/pubmed/23847399
http://dx.doi.org/10.6026/97320630009456

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