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Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon

Background. Spontaneous gas gangrene is a rare disease in which Clostridium septicum frequently can be detected. After an incubation period of 5–48 hours, a very painful swelling is accompanied by a rapidly spreading toxic-infectious clinical picture ultimately leading to septic shock and multiple o...

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Autores principales: Hartel, Maximilian, Kutup, Asad, Gehl, Axel, Zustin, Jozef, Grossterlinden, Lars G., Rueger, Johannes M., Lehmann, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705781/
https://www.ncbi.nlm.nih.gov/pubmed/23864974
http://dx.doi.org/10.1155/2013/216382
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author Hartel, Maximilian
Kutup, Asad
Gehl, Axel
Zustin, Jozef
Grossterlinden, Lars G.
Rueger, Johannes M.
Lehmann, Wolfgang
author_facet Hartel, Maximilian
Kutup, Asad
Gehl, Axel
Zustin, Jozef
Grossterlinden, Lars G.
Rueger, Johannes M.
Lehmann, Wolfgang
author_sort Hartel, Maximilian
collection PubMed
description Background. Spontaneous gas gangrene is a rare disease in which Clostridium septicum frequently can be detected. After an incubation period of 5–48 hours, a very painful swelling is accompanied by a rapidly spreading toxic-infectious clinical picture ultimately leading to septic shock and multiple organ failure. We present a case of a completely documented rare infectious disease with triage findings including initial vital signs, initial medical findings, and the emergency lab., radiological, intraoperative, histopathological, microbiological, and postmortem results. After initial diagnosis of the underlying disease, the patient has been immediately transferred to the operating theatre. The laboratory findings reflect the devastating effect of toxin α which is a toxin typically produced by C. septicum. The patient presented both an anaemia and a manifest coagulopathy as well as an onset of multiple organ failure. Despite the aggressive medical and surgical measures that have been taken, this patient could not be saved. Discussion. The case presented vividly emphasises the difficulty to identify these cases early enough to save a patient. This documentation may help health care providers to identify this life threatening disease as early as possible in future cases.
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spelling pubmed-37057812013-07-17 Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon Hartel, Maximilian Kutup, Asad Gehl, Axel Zustin, Jozef Grossterlinden, Lars G. Rueger, Johannes M. Lehmann, Wolfgang Case Rep Orthop Case Report Background. Spontaneous gas gangrene is a rare disease in which Clostridium septicum frequently can be detected. After an incubation period of 5–48 hours, a very painful swelling is accompanied by a rapidly spreading toxic-infectious clinical picture ultimately leading to septic shock and multiple organ failure. We present a case of a completely documented rare infectious disease with triage findings including initial vital signs, initial medical findings, and the emergency lab., radiological, intraoperative, histopathological, microbiological, and postmortem results. After initial diagnosis of the underlying disease, the patient has been immediately transferred to the operating theatre. The laboratory findings reflect the devastating effect of toxin α which is a toxin typically produced by C. septicum. The patient presented both an anaemia and a manifest coagulopathy as well as an onset of multiple organ failure. Despite the aggressive medical and surgical measures that have been taken, this patient could not be saved. Discussion. The case presented vividly emphasises the difficulty to identify these cases early enough to save a patient. This documentation may help health care providers to identify this life threatening disease as early as possible in future cases. Hindawi Publishing Corporation 2013 2013-06-20 /pmc/articles/PMC3705781/ /pubmed/23864974 http://dx.doi.org/10.1155/2013/216382 Text en Copyright © 2013 Maximilian Hartel et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hartel, Maximilian
Kutup, Asad
Gehl, Axel
Zustin, Jozef
Grossterlinden, Lars G.
Rueger, Johannes M.
Lehmann, Wolfgang
Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
title Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
title_full Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
title_fullStr Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
title_full_unstemmed Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
title_short Foudroyant Course of an Extensive Clostridium septicum Gas Gangrene in a Diabetic Patient with Occult Carcinoma of the Colon
title_sort foudroyant course of an extensive clostridium septicum gas gangrene in a diabetic patient with occult carcinoma of the colon
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705781/
https://www.ncbi.nlm.nih.gov/pubmed/23864974
http://dx.doi.org/10.1155/2013/216382
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