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Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature

Adderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and...

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Autores principales: Vanga, Rohini R., Bal, Bikram, Olden, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706063/
https://www.ncbi.nlm.nih.gov/pubmed/23864967
http://dx.doi.org/10.1155/2013/902892
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author Vanga, Rohini R.
Bal, Bikram
Olden, Kevin W.
author_facet Vanga, Rohini R.
Bal, Bikram
Olden, Kevin W.
author_sort Vanga, Rohini R.
collection PubMed
description Adderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and to our knowledge no cases have been reported in the English literature. Amphetamine is an ingredient of recreational drugs such as Ecstacy and is known to cause hepatotoxicity. We describe here the case of a 55-year-old woman who developed acute liver failure during the treatment of ADHD with Adderall. She presented to the emergency room with worsening abdominal pain, malaise, and jaundice requiring hospitalization. She had a past history of partial hepatic resection secondary to metastasis from colon cancer which was under remission at the time of presentation. She recovered after intensive monitoring and conservative management. Adderall should be used carefully in individuals with underlying liver conditions.
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spelling pubmed-37060632013-07-17 Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature Vanga, Rohini R. Bal, Bikram Olden, Kevin W. Case Rep Gastrointest Med Case Report Adderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and to our knowledge no cases have been reported in the English literature. Amphetamine is an ingredient of recreational drugs such as Ecstacy and is known to cause hepatotoxicity. We describe here the case of a 55-year-old woman who developed acute liver failure during the treatment of ADHD with Adderall. She presented to the emergency room with worsening abdominal pain, malaise, and jaundice requiring hospitalization. She had a past history of partial hepatic resection secondary to metastasis from colon cancer which was under remission at the time of presentation. She recovered after intensive monitoring and conservative management. Adderall should be used carefully in individuals with underlying liver conditions. Hindawi Publishing Corporation 2013 2013-06-23 /pmc/articles/PMC3706063/ /pubmed/23864967 http://dx.doi.org/10.1155/2013/902892 Text en Copyright © 2013 Rohini R. Vanga et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Vanga, Rohini R.
Bal, Bikram
Olden, Kevin W.
Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
title Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
title_full Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
title_fullStr Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
title_full_unstemmed Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
title_short Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature
title_sort adderall induced acute liver injury: a rare case and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706063/
https://www.ncbi.nlm.nih.gov/pubmed/23864967
http://dx.doi.org/10.1155/2013/902892
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