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Transcriptional and epigenetic signatures of zygotic genome activation during early drosophila embryogenesis

BACKGROUND: In all Metazoa, transcription is inactive during the first mitotic cycles after fertilisation. In Drosophila melanogaster, Zygotic Genome Activation (ZGA) occurs in two waves, starting respectively at mitotic cycles 8 (approximately 60 genes) and 14 (over a thousand genes). The regulator...

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Detalles Bibliográficos
Autores principales:	Darbo, Elodie, Herrmann, Carl, Lecuit, Thomas, Thieffry, Denis, van Helden, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706223/ https://www.ncbi.nlm.nih.gov/pubmed/23560912 http://dx.doi.org/10.1186/1471-2164-14-226

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