Cargando…
Modeling of celiac disease immune response and the therapeutic effect of potential drugs
BACKGROUND: Celiac disease (CD) is an autoimmune disorder that occurs in genetically predisposed people and is caused by a reaction to the gluten protein found in wheat, which leads to intestinal villous atrophy. Currently there is no drug for treatment of CD. The only known treatment is lifelong gl...
Autores principales: | Demin, Oleg O, Smirnov, Sergey V, Sokolov, Victor V, Cucurull-Sanchez, Lourdes, Pichardo-Almarza, Cesar, Flores, M Victoria, Benson, Neil, Demin, Oleg V |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706242/ https://www.ncbi.nlm.nih.gov/pubmed/23826972 http://dx.doi.org/10.1186/1752-0509-7-56 |
Ejemplares similares
-
Analysis of the efficacy of SGLT2 inhibitors using semi-mechanistic model
por: Demin, Oleg, et al.
Publicado: (2014) -
Regulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach
por: Karelina, Tatiana A, et al.
Publicado: (2012) -
From PK/PD to QSP: Understanding the Dynamic Effect of Cholesterol-Lowering Drugs on Atherosclerosis Progression and Stratified Medicine
por: Pichardo-Almarza, Cesar, et al.
Publicado: (2016) -
Studying the Progression of Amyloid Pathology and Its Therapy Using Translational Longitudinal Model of Accumulation and Distribution of Amyloid Beta
por: Karelina, Tatiana, et al.
Publicado: (2017) -
Receptor occupancy assessment and interpretation in terms of quantitative systems pharmacology: nivolumab case study
por: Shchelokov, Dmitry, et al.
Publicado: (2022)