Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management

G protein-coupled receptors (GPCRs) modulate a vast array of cellular processes. The current review gives an overview of the general characteristics of GPCRs and their role in physiological conditions. In addition, it describes the current knowledge of the physiological and pathophysiological functi...

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Detalles Bibliográficos
Autores principales: Leyva-Illades, Dinorah, DeMorrow, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706254/
https://www.ncbi.nlm.nih.gov/pubmed/23869178
http://dx.doi.org/10.2147/CMAR.S35175
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author Leyva-Illades, Dinorah
DeMorrow, Sharon
author_facet Leyva-Illades, Dinorah
DeMorrow, Sharon
author_sort Leyva-Illades, Dinorah
collection PubMed
description G protein-coupled receptors (GPCRs) modulate a vast array of cellular processes. The current review gives an overview of the general characteristics of GPCRs and their role in physiological conditions. In addition, it describes the current knowledge of the physiological and pathophysiological functions of GPR55, an orphan GPCR, and how it can be exploited as a therapeutic target to combat various cancers.
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spelling pubmed-37062542013-07-18 Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management Leyva-Illades, Dinorah DeMorrow, Sharon Cancer Manag Res Review G protein-coupled receptors (GPCRs) modulate a vast array of cellular processes. The current review gives an overview of the general characteristics of GPCRs and their role in physiological conditions. In addition, it describes the current knowledge of the physiological and pathophysiological functions of GPR55, an orphan GPCR, and how it can be exploited as a therapeutic target to combat various cancers. Dove Medical Press 2013-07-01 /pmc/articles/PMC3706254/ /pubmed/23869178 http://dx.doi.org/10.2147/CMAR.S35175 Text en © 2013 Leyva-Illades and DeMorrow, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Leyva-Illades, Dinorah
DeMorrow, Sharon
Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
title Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
title_full Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
title_fullStr Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
title_full_unstemmed Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
title_short Orphan G protein receptor GPR55 as an emerging target in cancer therapy and management
title_sort orphan g protein receptor gpr55 as an emerging target in cancer therapy and management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706254/
https://www.ncbi.nlm.nih.gov/pubmed/23869178
http://dx.doi.org/10.2147/CMAR.S35175
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