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Effects of Resveratrol and SIRT1 on PGC-1α Activity and Mitochondrial Biogenesis: A Reevaluation

It has been reported that feeding mice resveratrol activates AMPK and SIRT1 in skeletal muscle leading to deacetylation and activation of PGC-1α, increased mitochondrial biogenesis, and improved running endurance. This study was done to further evaluate the effects of resveratrol, SIRT1, and PGC-1α...

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Detalles Bibliográficos
Autores principales: Higashida, Kazuhiko, Kim, Sang Hyun, Jung, Su Ryun, Asaka, Meiko, Holloszy, John O., Han, Dong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706311/
https://www.ncbi.nlm.nih.gov/pubmed/23874150
http://dx.doi.org/10.1371/journal.pbio.1001603

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