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Chimeric antigen receptor-engineered T cells for cancer immunotherapy: progress and challenges
Recent years have witnessed much progress in both basic research and clinical trials regarding cancer immunotherapy with chimeric antigen receptor (CAR)-engineered T cells. The unique structure of CAR endows T cell tumor specific cytotoxicity and resistance to immunosuppressive microenvironment in c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706354/ https://www.ncbi.nlm.nih.gov/pubmed/23829929 http://dx.doi.org/10.1186/1756-8722-6-47 |