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GPR56 Functions Together with α3β1 Integrin in Regulating Cerebral Cortical Development

Loss of function mutations in GPR56, which encodes a G protein-coupled receptor, cause a specific human brain malformation called bilateral frontoparietal polymicrogyria (BFPP). Studies from BFPP postmortem brain tissue and Gpr56 knockout mice have previously showed that GPR56 deletion leads to brea...

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Detalles Bibliográficos
Autores principales: Jeong, Sung-Jin, Luo, Rong, Singer, Kathleen, Giera, Stefanie, Kreidberg, Jordan, Kiyozumi, Daiji, Shimono, Chisei, Sekiguchi, Kiyotoshi, Piao, Xianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706371/
https://www.ncbi.nlm.nih.gov/pubmed/23874761
http://dx.doi.org/10.1371/journal.pone.0068781