Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

We have previously reported a simple and customizable CRISPR (clustered regularly interspaced short palindromic repeats) RNA-guided Cas9 nuclease (RGN) system that can be used to efficiently and robustly introduce somatic indel mutations in endogenous zebrafish genes. Here we demonstrate that RGN-in...

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Detalles Bibliográficos
Autores principales: Hwang, Woong Y., Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L., Kaini, Prakriti, Sander, Jeffry D., Joung, J. Keith, Peterson, Randall T., Yeh, Jing-Ruey Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706373/
https://www.ncbi.nlm.nih.gov/pubmed/23874735
http://dx.doi.org/10.1371/journal.pone.0068708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706373/
https://www.ncbi.nlm.nih.gov/pubmed/23874735
http://dx.doi.org/10.1371/journal.pone.0068708

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