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A reliable and feasible qPCR strategy for titrating AAV vectors
BACKGROUND: Previous studies have revealed that traditional real-time quantitative PCR (qPCR) underestimates adeno-associated virus (AAV) titer. Because the inverted terminal repeat (ITR) exists in all AAV vectors, the only remaining element from the wild genome could form special configurations to...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Scientific Literature, Inc.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706409/ https://www.ncbi.nlm.nih.gov/pubmed/23828206 http://dx.doi.org/10.12659/MSMBR.883968 |