Cargando…

Resistance Mutations and CTL Epitopes in Archived HIV-1 DNA of Patients on Antiviral Treatment: Toward a New Concept of Vaccine

Eleven patients responding successfully to first-line antiretroviral therapy (ART) were investigated for proviral drug resistance mutations (DRMs) in RT by ultra-deep pyrosequencing (UDPS). After molecular typing of the class I alleles A and B, the CTL epitopes in the Gag, Nef and Pol regions of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Papuchon, Jennifer, Pinson, Patricia, Lazaro, Estibaliz, Reigadas, Sandrine, Guidicelli, Gwendaline, Taupin, Jean-Luc, Neau, Didier, Fleury, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706427/ https://www.ncbi.nlm.nih.gov/pubmed/23874854 http://dx.doi.org/10.1371/journal.pone.0069029

Ejemplares similares

Kinetics of HIV-1 CTL Epitopes Recognized by HLA I Alleles in HIV-Infected Individuals at Times near Primary Infection: The Provir/Latitude45 Study
por: Papuchon, Jennifer, et al.
Publicado: (2014)

Sanger and Next-Generation Sequencing data for characterization of CTL epitopes in archived HIV-1 proviral DNA
por: Tumiotto, Camille, et al.
Publicado: (2017)

Provir/Latitude 45 study: A step towards a multi-epitopic CTL vaccine designed on archived HIV-1 DNA and according to dominant HLA I alleles
por: Tumiotto, Camille, et al.
Publicado: (2019)

K65R in Subtype C HIV-1 Isolates from Patients Failing on a First-Line Regimen Including d4T or AZT: Comparison of Sanger and UDP Sequencing Data
por: Recordon-Pinson, Patricia, et al.
Publicado: (2012)

Molecular Characterization of HIV-1 CRF01_AE in Mekong Delta, Vietnam, and Impact of T-Cell Epitope Mutations on HLA Recognition (ANRS 12159)
por: Lazaro, Estibaliz, et al.
Publicado: (2011)

Prevalence and Evolution of Low Frequency HIV Drug Resistance Mutations Detected by Ultra Deep Sequencing in Patients Experiencing First Line Antiretroviral Therapy Failure
por: Vandenhende, Marie-Anne, et al.
Publicado: (2014)

Switch to Rilpivirine/Emtricitabine/Tenofovir Single-Tablet Regimen of Human Immunodeficiency Virus-1 RNA-Suppressed Patients, Agence Nationale de Recherches sur le SIDA et les Hépatites Virales CO3 Aquitaine Cohort, 2012–2014
por: Cazanave, Charles, et al.
Publicado: (2015)

Switching and emergence of CTL epitopes in HIV-1 infection
por: Han, Chungyong, et al.
Publicado: (2014)

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy
por: Recordon-Pinson, Patricia, et al.
Publicado: (2021)

Characterization of the novel HLA‐DQA1*02:01:14 allele by sequencing‐based typing
por: Cargou, Marine, et al.
Publicado: (2022)

Characterization of the novel HLA‐DPA1*02:01:21 allele by sequencing‐based typing
por: Cargou, Marine, et al.
Publicado: (2022)

The Emerging Role for CTL Epitope Specificity in HIV Cure Efforts
por: Kaseke, Clarety, et al.
Publicado: (2021)

Characterization of the novel HLA‐DQA1*01:89 allele by sequencing‐based typing
por: Cargou, Marine, et al.
Publicado: (2022)

CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope
por: Cardinaud, Sylvain, et al.
Publicado: (2011)

Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens
por: Demachi-Okamura, Ayako, et al.
Publicado: (2012)

ART-Treated Patients Exhibit an Adaptive Immune Response against the HFVAC Peptides, a Potential HIV-1 Therapeutic Vaccine (Provir/Latitude45 Study)
por: Fleury, Hervé, et al.
Publicado: (2020)

The Necrotic Signal Induced by Mycophenolic Acid Overcomes Apoptosis-Resistance in Tumor Cells
por: Guidicelli, Gwendaline, et al.
Publicado: (2009)

Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine
por: Chakraborty, Sajib, et al.
Publicado: (2014)

The distribution of CTL epitopes in HIV-1 appears to be random, and similar to that of other proteomes
por: Schmid, Boris V, et al.
Publicado: (2009)

Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection
por: Shimizu, Akihisa, et al.
Publicado: (2013)

Rational Design of a Pan-Coronavirus Vaccine Based on Conserved CTL Epitopes
por: Li, Minchao, et al.
Publicado: (2021)

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes
por: Garcia-Bates, Tatiana M., et al.
Publicado: (2021)

Frequent associations between CTL and T-Helper epitopes in HIV-1 genomes and implications for multi-epitope vaccine designs
por: Paul, Sinu, et al.
Publicado: (2010)

Cytotoxic T lymphocytes (CTL) against a transforming gene product select for transformed cells with point mutations within sequences encoding CTL recognition epitopes
Publicado: (1992)

Identification of Novel HLA-A*0201-Restricted CTL Epitopes in Chinese Vitiligo Patients
por: Cui, Tingting, et al.
Publicado: (2016)

Within-Epitope Interactions Can Bias CTL Escape Estimation in Early HIV Infection
por: Garcia, Victor, et al.
Publicado: (2017)

Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV-2 strains
por: Welner, Simon, et al.
Publicado: (2017)

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses
por: Wu, Ting, et al.
Publicado: (2019)

Evolutionary conservation and positive selection of influenza A nucleoprotein CTL epitopes for universal vaccination
por: McGee, Michael C., et al.
Publicado: (2022)

An alloresponse in humans is dominated by cytotoxic T lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: implications for graft-versus-host disease
Publicado: (1994)

Clusters versus Affinity-Based Approaches in F. tularensis Whole Genome Search of CTL Epitopes
por: Zvi, Anat, et al.
Publicado: (2012)

OA06-03. Dynamics of CTL epitope escape and reversion in an African subtype C cohort
por: Schaefer, M, et al.
Publicado: (2009)

A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: Potential impact on CTL epitopes
por: Srinivasan, Alagarsamy, et al.
Publicado: (2008)

HLA-A*0201-restricted CTL epitope of a novel osteosarcoma antigen, papillomavirus binding factor
por: Tsukahara, Tomohide, et al.
Publicado: (2009)

Screening and Identification of an H-2K(b)-Restricted CTL Epitope within the Glycoprotein of Hantaan Virus
por: Ma, Rui-xue, et al.
Publicado: (2016)

Identification of a dominant CD8(+) CTL epitope in the SARS-associated coronavirus 2 spike protein
por: Muraoka, Daisuke, et al.
Publicado: (2020)

Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein
por: Jiang, Sheng, et al.
Publicado: (2022)

Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis
por: Lin, Yan, et al.
Publicado: (2021)

Prospective Measures of Adherence by Questionnaire, Low Immunosuppression and Graft Outcome in Kidney Transplantation
por: Prezelin-Reydit, Mathilde, et al.
Publicado: (2021)

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells
por: Casartelli, Nicoletta, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_i77kknl96k9fe8ri056bfb31k0