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Intrinsic TNF/TNFR2 Interactions Fine-Tune the CD8 T Cell Response to Respiratory Influenza Virus Infection in Mice

TNF is an important inflammatory mediator and a target for intervention. TNF is produced by many cell types and is involved in innate inflammation as well as adaptive immune responses. CD8 T cells produce TNF and can also respond to TNF. Deficiency of TNF or TNFR2 has been shown to affect anti-viral...

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Detalles Bibliográficos
Autores principales: Wortzman, Michael E., Lin, Gloria H. Y., Watts, Tania H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706430/
https://www.ncbi.nlm.nih.gov/pubmed/23874808
http://dx.doi.org/10.1371/journal.pone.0068911