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Extracellular ATP Released by Osteoblasts Is A Key Local Inhibitor of Bone Mineralisation
Previous studies have shown that exogenous ATP (>1µM) prevents bone formation in vitro by blocking mineralisation of the collagenous matrix. This effect is thought to be mediated via both P2 receptor-dependent pathways and a receptor-independent mechanism (hydrolysis of ATP to produce the mineral...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706437/ https://www.ncbi.nlm.nih.gov/pubmed/23874866 http://dx.doi.org/10.1371/journal.pone.0069057 |