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Zoledronic Acid Enhances Lipopolysaccharide-Stimulated Proinflammatory Reactions through Controlled Expression of SOCS1 in Macrophages

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a serious side effect of nitrogen-containing bisphosphonate (NBP) use. Many studies have shown that BRONJ is limited to the jawbone and does not occur in the other bones. We hypothesized that BRONJ is related to local bacterial iections and...

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Detalles Bibliográficos
Autores principales: Muratsu, Daichi, Yoshiga, Daigo, Taketomi, Takaharu, Onimura, Tomohiro, Seki, Yoshihiro, Matsumoto, Akinobu, Nakamura, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706453/
https://www.ncbi.nlm.nih.gov/pubmed/23874464
http://dx.doi.org/10.1371/journal.pone.0067906