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COX-2-Derived Prostanoids and Oxidative Stress Additionally Reduce Endothelium-Mediated Relaxation in Old Type 2 Diabetic Rats

Endothelial dysfunction in resistance arteries alters end organ perfusion in type 2 diabetes. Superoxides and cyclooxygenase-2 (COX-2) derivatives have been shown separately to alter endothelium-mediated relaxation in aging and diabetes but their role in the alteration of vascular tone in old diabet...

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Detalles Bibliográficos
Autores principales:	Vessières, Emilie, Guihot, Anne-Laure, Toutain, Bertrand, Maquigneau, Maud, Fassot, Céline, Loufrani, Laurent, Henrion, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706542/ https://www.ncbi.nlm.nih.gov/pubmed/23874545 http://dx.doi.org/10.1371/journal.pone.0068217

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