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Indoxyl Sulfate Down-Regulates SLCO4C1 Transporter through Up-Regulation of GATA3

The accumulated uremic toxins inhibit the expression of various renal transporters and this inhibition may further reduce renal function and subsequently cause the accumulation of uremic toxins. However, the precise mechanism of the nephrotoxicity of uremic toxins on renal transport has been poorly...

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Detalles Bibliográficos
Autores principales: Akiyama, Yasutoshi, Kikuchi, Koichi, Saigusa, Daisuke, Suzuki, Takehiro, Takeuchi, Yoichi, Mishima, Eikan, Yamamoto, Yasuaki, Ishida, Ayako, Sugawara, Daiki, Jinno, Daisuke, Shima, Hisato, Toyohara, Takafumi, Suzuki, Chitose, Souma, Tomokazu, Moriguchi, Takashi, Tomioka, Yoshihisa, Ito, Sadayoshi, Abe, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706553/
https://www.ncbi.nlm.nih.gov/pubmed/23874392
http://dx.doi.org/10.1371/journal.pone.0066518