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β5 Integrin Up-Regulation in Brain-Derived Neurotrophic Factor Promotes Cell Motility in Human Chondrosarcoma

Chondrosarcoma is a primary malignant bone cancer, with a potent capacity to invade locally and cause distant metastasis; it has a poor prognosis and shows a predilection for metastasis to the lungs. Brain derived neurotrophic factor (BDNF) is a small-molecule protein from the neurotrophin family of...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Yang, Chen, Hui-Jye, Li, Te-Mao, Fong, Yi-Chin, Liu, Shan-Chi, Chen, Po-Chun, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706611/
https://www.ncbi.nlm.nih.gov/pubmed/23874483
http://dx.doi.org/10.1371/journal.pone.0067990