Cargando…

Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia–reperfusion injury

INTRODUCTION: This study tested the hypothesis that cyclosporine (CsA)-supported syngeneic adipose-derived mesenchymal stem cell (ADMSC) therapy offered superior attenuation of acute ischemia–reperfusion (IR) kidney injury to either therapy alone. METHODS: Adult Sprague–Dawley rats (n = 40) were equ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yen-Ta, Yang, Chih-Chau, Zhen, Yen-Yi, Wallace, Christopher Glenn, Yang, Jenq-Lin, Sun, Cheuk-Kwan, Tsai, Tzu-Hsien, Sheu, Jiunn-Jye, Chua, Sarah, Chang, Chia-Lo, Cho, Chung-Lung, Leu, Steve, Yip, Hon-Kan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706768/ https://www.ncbi.nlm.nih.gov/pubmed/23726287 http://dx.doi.org/10.1186/scrt212

Ejemplares similares

Combination of cilostazol and clopidogrel attenuates Rat critical limb ischemia
por: Sheu, Jiunn-Jye, et al.
Publicado: (2012)

Inhibition of dipeptidyl peptidase-IV enzyme activity protects against myocardial ischemia-reperfusion injury in rats
por: Chua, Sarah, et al.
Publicado: (2014)

Administered circulating microparticles derived from lung cancer patients markedly improved angiogenesis, blood flow and ischemic recovery in rat critical limb ischemia
por: Sheu, Jiunn-Jye, et al.
Publicado: (2015)

Combined Therapy with SS31 and Mitochondria Mitigates Myocardial Ischemia-Reperfusion Injury in Rats
por: Lee, Fan-Yen, et al.
Publicado: (2018)

Intra-coronary administration of tacrolimus markedly attenuates infarct size and preserves heart function in porcine myocardial infarction
por: Chua, Sarah, et al.
Publicado: (2012)

Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke
por: Yuen, Chun-Man, et al.
Publicado: (2011)

Impact of obesity control on circulating level of endothelial progenitor cells and angiogenesis in response to ischemic stimulation
por: Chen, Yung-Lung, et al.
Publicado: (2012)

Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction
por: Chen, Yen-Ta, et al.
Publicado: (2013)

Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction
por: Chen, Yen-Ta, et al.
Publicado: (2011)

Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia
por: Sun, Cheuk-Kwan, et al.
Publicado: (2013)

Innate immune response after acute myocardial infarction and pharmacomodulatory action of tacrolimus in reducing infarct size and preserving myocardial integrity
por: Sheu, Jiunn-Jye, et al.
Publicado: (2013)

Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model
por: Sun, Cheuk-Kwan, et al.
Publicado: (2014)

Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model
por: Sun, Cheuk-Kwan, et al.
Publicado: (2011)

Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy
por: Yen, Chia-Hung, et al.
Publicado: (2012)

DPP-4 enzyme deficiency protects kidney from acute ischemia-reperfusion injury: role for remote intermittent bowel ischemia-reperfusion preconditioning
por: Chen, Yen-Ta, et al.
Publicado: (2017)

MicroRNA-214 modulates the senescence of vascular smooth muscle cells in carotid artery stenosis
por: Chen, Yi-Ling, et al.
Publicado: (2020)

Extracorporeal Shock Wave-Supported Adipose-Derived Fresh Stromal Vascular Fraction Preserved Left Ventricular (LV) Function and Inhibited LV Remodeling in Acute Myocardial Infarction in Rat
por: Sung, Pei-Hsun, et al.
Publicado: (2018)

Xenogeneic human umbilical cord-derived mesenchymal stem cells reduce mortality in rats with acute respiratory distress syndrome complicated by sepsis
por: Lee, Fan-Yen, et al.
Publicado: (2017)

Levels and values of lipoprotein-associated phospholipase A(2), galectin-3, RhoA/ROCK, and endothelial progenitor cells in critical limb ischemia: pharmaco-therapeutic role of cilostazol and clopidogrel combination therapy
por: Sheu, Jiunn-Jye, et al.
Publicado: (2014)

Extracorporeal Shock Wave Therapy Reverses Ischemia-Related Left Ventricular Dysfunction and Remodeling: Molecular-Cellular and Functional Assessment
por: Fu, Morgan, et al.
Publicado: (2011)

Therapeutic Potential of Tacrolimus on Acute Myocardial Infarction in Minipigs: Analysis with Serial Cardiac Magnetic Resonance and Changes at Histological and Protein Levels
por: Ko, Sheung-Fat, et al.
Publicado: (2014)

Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy
por: Lin, Yu-Chun, et al.
Publicado: (2010)

Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation
por: Chang, Chia-Lo, et al.
Publicado: (2012)

Extracorporeal shock wave treatment attenuated left ventricular dysfunction and remodeling in mini-pig with cardiorenal syndrome
por: Sheu, Jiunn-Jye, et al.
Publicado: (2017)

Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats
por: Leu, Steve, et al.
Publicado: (2010)

Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice
por: Wang, Hui-Ting, et al.
Publicado: (2012)

Effective protection against acute respiratory distress syndrome/sepsis injury by combined adipose-derived mesenchymal stem cells and preactivated disaggregated platelets
por: Chen, Chih-Hung, et al.
Publicado: (2017)

Obesity suppresses circulating level and function of endothelial progenitor cells and heart function
por: Tsai, Tzu-Hsien, et al.
Publicado: (2012)

Broken-crescent sign at CT indicates impending aortic rupture in patients with acute aortic intramural hematoma
por: Ko, Sheung-Fat, et al.
Publicado: (2020)

Cellular Prion Protein Is Essential for Myocardial Regeneration but Not the Recovery of Left Ventricular Function from Apical Ballooning
por: Sheu, Jiunn-Jye, et al.
Publicado: (2022)

TRICKS Magnetic Resonance Angiography at 3-Tesla for Assessing Whole Lower Extremity Vascular Tree in Patients with High-Grade Critical Limb Ischemia: DSA and TASC II Guidelines Correlations
por: Ko, Sheung-Fat, et al.
Publicado: (2012)

Myocardium-derived conditioned medium improves left ventricular function in rodent acute myocardial infarction
por: Leu, Steve, et al.
Publicado: (2011)

Effect of erythropoietin therapy on clinical outcome in patients after acute ischemic stroke: a debatable issue
por: Yuen, Chun-Man, et al.
Publicado: (2011)

tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis
por: Leu, Steve, et al.
Publicado: (2016)

Intravenous administration of iPS‐MSC(SPIONs) mobilized into CKD parenchyma and effectively preserved residual renal function in CKD rat
por: Sheu, Jiunn‐Jye, et al.
Publicado: (2020)

Comparison of acute versus convalescent stage high-sensitivity C-Reactive protein level in predicting clinical outcome after acute ischemic stroke and impact of erythropoietin
por: Yeh, Kuo-Ho, et al.
Publicado: (2012)

Extracorporeal shockwave against inflammation mediated by GPR120 receptor in cyclophosphamide-induced rat cystitis model
por: Chen, Yi-Ling, et al.
Publicado: (2018)

Impact of One Versus Two Consecutive Doses of Endothelial Cells (EPCs) and EPCs-Derived Condition Medium on Protecting Myocardium from Acute Ischemia-Reperfusion Injury in Rat
por: Yeh, Jui-Ning, et al.
Publicado: (2021)

Double overexpression of miR-19a and miR-20a in induced pluripotent stem cell-derived mesenchymal stem cells effectively preserves the left ventricular function in dilated cardiomyopathic rat
por: Sheu, Jiunn-Jye, et al.
Publicado: (2021)

Levels and values of circulating endothelial progenitor cells, soluble angiogenic factors, and mononuclear cell apoptosis in liver cirrhosis patients
por: Chen, Chih-Hung, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_hokojjjthscio4emmkp75fc6b0