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Genes and pathways underlying regional and cell type changes in Alzheimer's disease

BACKGROUND: Transcriptional studies suggest Alzheimer's disease (AD) involves dysfunction of many cellular pathways, including synaptic transmission, cytoskeletal dynamics, energetics, and apoptosis. Despite known progression of AD pathologies, it is unclear how such striking regional vulnerabi...

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Detalles Bibliográficos
Autores principales:	Miller, Jeremy A, Woltjer, Randall L, Goodenbour, Jeff M, Horvath, Steve, Geschwind, Daniel H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706780/ https://www.ncbi.nlm.nih.gov/pubmed/23705665 http://dx.doi.org/10.1186/gm452

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