The effect of cyclodextrin-solubilized curcuminoids on amyloid plaques in Alzheimer transgenic mice: brain uptake and metabolism after intravenous and subcutaneous injection

INTRODUCTION: Curcuminoids may improve pathological conditions associated with Alzheimer's disease. However, their therapeutic potential is limited by their exceedingly low bioavailability after oral administration. A method to deliver solubilized curcuminoids by injection was evaluated in Alzh...

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Detalles Bibliográficos
Autores principales: Quitschke, Wolfgang W, Steinhauff, Nicole, Rooney, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706801/
https://www.ncbi.nlm.nih.gov/pubmed/23537472
http://dx.doi.org/10.1186/alzrt170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706801/
https://www.ncbi.nlm.nih.gov/pubmed/23537472
http://dx.doi.org/10.1186/alzrt170

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