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The effect of cyclodextrin-solubilized curcuminoids on amyloid plaques in Alzheimer transgenic mice: brain uptake and metabolism after intravenous and subcutaneous injection

INTRODUCTION: Curcuminoids may improve pathological conditions associated with Alzheimer's disease. However, their therapeutic potential is limited by their exceedingly low bioavailability after oral administration. A method to deliver solubilized curcuminoids by injection was evaluated in Alzh...

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Detalles Bibliográficos
Autores principales:	Quitschke, Wolfgang W, Steinhauff, Nicole, Rooney, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706801/ https://www.ncbi.nlm.nih.gov/pubmed/23537472 http://dx.doi.org/10.1186/alzrt170

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