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The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors

INTRODUCTION: Dysregulation of the insulin-like growth factor-1 receptor (IGF-1R)/phosphatidylinositol-3-kinase (PI3K)/Akt pathway was shown to correlate with breast cancer disease progression. Cancer stem cells are a subpopulation within cancer cells that participate in tumor initiation, radio/chem...

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Detalles Bibliográficos
Autores principales:	Chang, Wen-Wei, Lin, Ruey-Jen, Yu, John, Chang, Wen-Ying, Fu, Chiung-Hui, Lai, Alan Chuan-Ying, Yu, Jyh-Cherng, Yu, Alice L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706809/ https://www.ncbi.nlm.nih.gov/pubmed/23663564 http://dx.doi.org/10.1186/bcr3423

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