Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitment

INTRODUCTION: Differentiation of vascular endothelial cells (ECs) in clinically relevant numbers for injection into ischaemic areas could offer therapeutic potential in the treatment of cardiovascular conditions, including myocardial infarction, peripheral vascular disease and stroke. While we and o...

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Detalles Bibliográficos
Autores principales: Howard, Lynsey, Mackenzie, Ruth M, Pchelintsev, Nikolay A, McBryan, Tony, McClure, John D, McBride, Martin W, Kane, Nicole M, Adams, Peter D, Milligan, Graeme, Baker, Andrew H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706826/
https://www.ncbi.nlm.nih.gov/pubmed/23618383
http://dx.doi.org/10.1186/scrt192

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