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Steroid responses in sepsis: some novel thinking that may provide new insight
Glucocorticoid use in sepsis is controversial. In contrast to other extracellular signaling molecules, glucocorticoid receptors (GRs) are intra-cytoplasmic. Several GR isoforms have been identified. A study in Critical Care Forum suggests that sepsis alters the abundance of the dominant negative GRβ...
Autor principal: | Deutschman, Clifford S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706853/ https://www.ncbi.nlm.nih.gov/pubmed/23826670 http://dx.doi.org/10.1186/cc12723 |
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