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Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneurons
INTRODUCTION: The use of immortalized neural stem cells either as models of neural development in vitro or as cellular therapies in central nervous system (CNS) disorders has been controversial. This controversy has centered on the capacity of immortalized cells to retain characteristic features of...
Autores principales: | Cocks, Graham, Romanyuk, Nataliya, Amemori, Takashi, Jendelova, Pavla, Forostyak, Oksana, Jeffries, Aaron R, Perfect, Leo, Thuret, Sandrine, Dayanithi, Govindan, Sykova, Eva, Price, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706922/ https://www.ncbi.nlm.nih.gov/pubmed/23759128 http://dx.doi.org/10.1186/scrt220 |
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