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The dichotomy of inhibiting nuclear factor kappa-B in pneumonia
Activation of nuclear factor kappa-B (NF-κB) results in its translocation from the cytoplasm to the nucleus and binding to the promoters of a large number of genes, including those encoding proinflammatory cytokines and other mediators that can contribute to organ system dysfunction in severe infect...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707031/ https://www.ncbi.nlm.nih.gov/pubmed/23759070 http://dx.doi.org/10.1186/cc12722 |