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New insights into store-independent Ca(2+) entry: secretory pathway calcium ATPase 2 in normal physiology and cancer

Recent studies in secretory pathway calcium ATPases (SPCA) revealed novel functions of SPCA2 in interacting with store-operated Ca(2+) channel Orai1 and inducing Ca(2+) influx at the cell surface. Importantly, SPCA2-mediated Ca(2+) signaling is uncoupled from its conventional role of Ca(2+)-ATPase a...

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Detalles Bibliográficos
Autores principales:	Feng, Ming-Ye, Rao, Rajini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707068/ https://www.ncbi.nlm.nih.gov/pubmed/23670239 http://dx.doi.org/10.1038/ijos.2013.23

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