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Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis

Delay of diagnosis of primary adrenal insufficiency (PAI) leads to adrenal crisis which is potentially lethal complication. The objective of our work was an assessment whether the establishment of diagnosis of adrenocortical insufficiency in Poland is so much delayed as assessed in the past. We have...

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Detalles Bibliográficos
Autores principales: Papierska, Lucyna, Rabijewski, Michał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707239/
https://www.ncbi.nlm.nih.gov/pubmed/23864857
http://dx.doi.org/10.1155/2013/482370
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author Papierska, Lucyna
Rabijewski, Michał
author_facet Papierska, Lucyna
Rabijewski, Michał
author_sort Papierska, Lucyna
collection PubMed
description Delay of diagnosis of primary adrenal insufficiency (PAI) leads to adrenal crisis which is potentially lethal complication. The objective of our work was an assessment whether the establishment of diagnosis of adrenocortical insufficiency in Poland is so much delayed as assessed in the past. We have analysed data from 60 patients with diagnosis of PAI established in our department during the past 12 years and who are still under our care. We found that the time to diagnosis of primary adrenal insufficiency in Poland exceeds 3 months in every patient and 6 months in patients admitted with symptoms of adrenal crisis. Forty-four percent of patients were diagnosed only just after the hospitalisation due to crisis, despite the evident signs and symptoms of PAI. Lack of appetite and loss of body weight occurred in all patients and for that reason a diagnosis of chronic gastric and duodenal ulcer disease was the most often incorrect diagnosis. After the proper diagnosis and treatment, in the course of 1–11 years of observation, there was only 6 imminent adrenal crises in 5 patients. Our results indicated that training of primary care physicians in the field of recognising and treatment of adrenal insufficiency is still essential.
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spelling pubmed-37072392013-07-17 Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis Papierska, Lucyna Rabijewski, Michał Int J Endocrinol Research Article Delay of diagnosis of primary adrenal insufficiency (PAI) leads to adrenal crisis which is potentially lethal complication. The objective of our work was an assessment whether the establishment of diagnosis of adrenocortical insufficiency in Poland is so much delayed as assessed in the past. We have analysed data from 60 patients with diagnosis of PAI established in our department during the past 12 years and who are still under our care. We found that the time to diagnosis of primary adrenal insufficiency in Poland exceeds 3 months in every patient and 6 months in patients admitted with symptoms of adrenal crisis. Forty-four percent of patients were diagnosed only just after the hospitalisation due to crisis, despite the evident signs and symptoms of PAI. Lack of appetite and loss of body weight occurred in all patients and for that reason a diagnosis of chronic gastric and duodenal ulcer disease was the most often incorrect diagnosis. After the proper diagnosis and treatment, in the course of 1–11 years of observation, there was only 6 imminent adrenal crises in 5 patients. Our results indicated that training of primary care physicians in the field of recognising and treatment of adrenal insufficiency is still essential. Hindawi Publishing Corporation 2013 2013-06-24 /pmc/articles/PMC3707239/ /pubmed/23864857 http://dx.doi.org/10.1155/2013/482370 Text en Copyright © 2013 L. Papierska and M. Rabijewski. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Papierska, Lucyna
Rabijewski, Michał
Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis
title Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis
title_full Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis
title_fullStr Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis
title_full_unstemmed Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis
title_short Delay in Diagnosis of Adrenal Insufficiency Is a Frequent Cause of Adrenal Crisis
title_sort delay in diagnosis of adrenal insufficiency is a frequent cause of adrenal crisis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707239/
https://www.ncbi.nlm.nih.gov/pubmed/23864857
http://dx.doi.org/10.1155/2013/482370
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