Reishi Protein LZ-8 Induces FOXP3(+) Treg Expansion via a CD45-Dependent Signaling Pathway and Alleviates Acute Intestinal Inflammation in Mice

LZ-8, an immunomodulatory protein isolated from Ganoderma lucidum (also known as Ling-Zhi or Reishi), has been shown to promote cell proliferation and IL-2 production in T cells. In this study, we show that LZ-8 induces the expansion of both murine and human CD4(+) T cells into FOXP3(+) regulatory T...

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Detalles Bibliográficos
Autores principales: Hsu, Hsien-Yeh, Kuan, Yen-Chou, Lin, Tung-Yi, Tsao, Shu-Ming, Hsu, Jason, Ma, Li-Juan, Sheu, Fuu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707273/
https://www.ncbi.nlm.nih.gov/pubmed/23864893
http://dx.doi.org/10.1155/2013/513542

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