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Molecular Recognition and Specific Interactions for Biosensing Applications

Molecular recognition and specific interactions are reliable and versatile routes for site-specific and well-oriented immobilization of functional biomolecules on surfaces. The control of surface properties via the molecular recognition and specific interactions at the nanoscale is a key element for...

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Detalles Bibliográficos
Autores principales: Kim, Dong Chung, Kang, Dae Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707470/
https://www.ncbi.nlm.nih.gov/pubmed/27873889
http://dx.doi.org/10.3390/s8106605
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author Kim, Dong Chung
Kang, Dae Joon
author_facet Kim, Dong Chung
Kang, Dae Joon
author_sort Kim, Dong Chung
collection PubMed
description Molecular recognition and specific interactions are reliable and versatile routes for site-specific and well-oriented immobilization of functional biomolecules on surfaces. The control of surface properties via the molecular recognition and specific interactions at the nanoscale is a key element for the nanofabrication of biosensors with high sensitivity and specificity. This review intends to provide a comprehensive understanding of the molecular recognition- and specific interaction-mediated biosensor fabrication routes that leads to biosensors with well-ordered and controlled structures on both nanopatterned surfaces and nanomaterials. Herein self-assembly of the biomolecules via the molecular recognition and specific interactions on nanoscaled surfaces as well as nanofabrication techniques of the biomolecules for biosensor architecture are discussed. We also describe the detection of molecular recognition- and specific interaction-mediated molecular binding as well as advantages of nanoscale detection.
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spelling pubmed-37074702013-07-10 Molecular Recognition and Specific Interactions for Biosensing Applications Kim, Dong Chung Kang, Dae Joon Sensors (Basel) Review Molecular recognition and specific interactions are reliable and versatile routes for site-specific and well-oriented immobilization of functional biomolecules on surfaces. The control of surface properties via the molecular recognition and specific interactions at the nanoscale is a key element for the nanofabrication of biosensors with high sensitivity and specificity. This review intends to provide a comprehensive understanding of the molecular recognition- and specific interaction-mediated biosensor fabrication routes that leads to biosensors with well-ordered and controlled structures on both nanopatterned surfaces and nanomaterials. Herein self-assembly of the biomolecules via the molecular recognition and specific interactions on nanoscaled surfaces as well as nanofabrication techniques of the biomolecules for biosensor architecture are discussed. We also describe the detection of molecular recognition- and specific interaction-mediated molecular binding as well as advantages of nanoscale detection. Molecular Diversity Preservation International (MDPI) 2008-10-23 /pmc/articles/PMC3707470/ /pubmed/27873889 http://dx.doi.org/10.3390/s8106605 Text en © 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Kim, Dong Chung
Kang, Dae Joon
Molecular Recognition and Specific Interactions for Biosensing Applications
title Molecular Recognition and Specific Interactions for Biosensing Applications
title_full Molecular Recognition and Specific Interactions for Biosensing Applications
title_fullStr Molecular Recognition and Specific Interactions for Biosensing Applications
title_full_unstemmed Molecular Recognition and Specific Interactions for Biosensing Applications
title_short Molecular Recognition and Specific Interactions for Biosensing Applications
title_sort molecular recognition and specific interactions for biosensing applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707470/
https://www.ncbi.nlm.nih.gov/pubmed/27873889
http://dx.doi.org/10.3390/s8106605
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