High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications

MiRNAs are discussed as diagnostic and therapeutic molecules. However, effective miRNA drug treatments with miRNAs are, so far, hampered by the complexity of the miRNA networks. To identify potential miRNA drugs in colorectal cancer, we profiled miRNA and mRNA expression in matching normal, tumor an...

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Detalles Bibliográficos
Autores principales: Röhr, Christina, Kerick, Martin, Fischer, Axel, Kühn, Alexander, Kashofer, Karl, Timmermann, Bernd, Daskalaki, Andriani, Meinel, Thomas, Drichel, Dmitriy, Börno, Stefan T., Nowka, Anja, Krobitsch, Sylvia, McHardy, Alice C., Kratsch, Christina, Becker, Tim, Wunderlich, Andrea, Barmeyer, Christian, Viertler, Christian, Zatloukal, Kurt, Wierling, Christoph, Lehrach, Hans, Schweiger, Michal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707605/
https://www.ncbi.nlm.nih.gov/pubmed/23874421
http://dx.doi.org/10.1371/journal.pone.0067461

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